Principal Investigators Leading the STRIDE Study
SHALENDER BHASIN, MD
Brigham and Women’s Hospital, Harvard Medical School, Boston
Professor of Medicine Harvard Medical School
Director, Center for Clinical Investigation
Director, Research Program in Men’s Health: Aging and Metabolism
Director, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women’s Hospital
Dr. Bhasin is the Director of the Center for Clinical Investigation and of the Research Program in Men’s Health: Aging and Metabolism. He also serves as the Director of the NIA-funded Boston Claude D. Pepper Older Americans Independence Center for Function Promoting Therapies at the Brigham and Women’s Hospital. He received his MD from the All India Institute of Medical Sciences in New Delhi, India, residency training at Northwestern University Medical School and fellowship training in Endocrinology and Nutrition at Harbor-UCLA Medical Center in Los Angeles, CA.
Dr. Bhasin is an internationally recognized expert in human aging, clinical trials of function promoting therapies for older adults, functional decline in aging, and testosterone biology. He chaired the Endocrine Society’s Expert Panel for the development of Guidelines for Testosterone Therapy. He is a translational researcher, with over 250 peer-reviewed manuscripts, 130 reviews and book chapters. Dr. Bhasin’s research has led to new applications of androgens and selective androgen receptor modulators. His pioneering research in androgen biology and anabolic therapies for aging-associated sarcopenia has been supported by several NIH-funded grants.
Dr. Bhasin has been the recipient of numerous teaching and research awards. He has served as: Associate Editor of the JCEM; Chair of the Clinical Guidelines Committee of the Endocrine Society; Chair of the Clinical Guidelines Panel of the Endocrine Society for diagnosis and treatment of hypogonadism; and Chair of American Board of Internal Medicine Endocrinology and Metabolism Board. He has been selected as one of the Best Doctors in America by Castle Connolly and by Boston Magazine. He is the recipient of the 2015 Outstanding Clinical Investigator Award of the Endocrine Society.
THOMAS GILL, MD
Yale School of Medicine, New Haven, Connecticut
Humana Professor of Medicine (Geriatrics) and Professor of Epidemiology (Chronic Diseases) and of Investigative Medicine
Director, Yale Program on Aging
Director, Claude D. Pepper Older Americans Independence Center at Yale
Director, Yale Training Program in Geriatric Clinical Epidemiology and Aging Related Research
Dr. Gill is Director of the Program on Aging and Claude D. Pepper Older Americans Independence Center at Yale. He received his medical degree at the University of Chicago’s Pritzker School of Medicine and his housestaff training in Internal Medicine at the University of Washington in Seattle, where he was Chief Resident. Dr. Gill received his research training in clinical epidemiology as a Robert Wood Johnson (RWJ) Clinical Scholar at Yale, and he joined the faculty in 1994 after completing an additional year as a geriatrics fellow. Dr. Gill is the author of more than 190 published reports and the recipient of numerous prestigious awards, including a MERIT Award and a Leadership Award from the National Institute on Aging.
During the past 20 years, Dr. Gill has done groundbreaking research on the epidemiology and prevention of disability, a challenging and complex problem of immense importance to older persons, their families and society. He directs the Center on Disability and Disabling Disorders, which conducts longitudinal studies and clinical trials to enhance the scientific knowledge base of the disablement process and to rigorously evaluate promising intervention strategies. The Center includes an expanding number of clinical investigators, across disciplines, who are pursuing aging research related to disability and disabling disorders. This includes functional assessment in general as well as the functional consequences of highly prevalent disease-specific conditions such as arthritis, heart failure, chronic lung disease, diabetes, depression, and dementia. Dr. Gill’s overarching goal is to translate findings from his longitudinal studies and clinical trials to promote the functional independence of older persons in an aging society.
DAVID REUBEN, MD
David Geffen School of Medicine at the University of California, Los Angeles
Chief, Geriatric Medicine UCLA Center for Health Sciences
Program Director, Alzheimer’s and Dementia Care Program
Archstone Foundation Chair and Professor at the David Geffen School of Medicine at UCLA
Director of the UCLA Claude D. Pepper Older Americans Independence Center
Dr. Reuben is Director, Multicampus Program in Geriatrics Medicine and Gerontology and Chief, Division of Geriatrics at the University of California, Los Angeles (UCLA) Center for Health Sciences. He is the Archstone Foundation Chair and Professor at the David Geffen School of Medicine at UCLA and Director of the UCLA Claude D. Pepper Older Americans Independence Center and the UCLA Alzheimer’s and Dementia Care program.
He sustains professional interests in clinical care, education, research and administrative aspects of geriatrics, maintaining a clinical primary care practice of frail older persons and attending on inpatient and geriatric psychiatry units at UCLA. He has won 7 awards for excellence in teaching. Dr. Reuben’s current research interests include redesigning the office visit to improve health care quality and co-management with nurse practitioners to improve health care quality. His bibliography includes more than 190 peer-reviewed publications in medical journals, 33 books and numerous chapters. He is lead author of the widely distributed book, Geriatrics at Your Fingertips.
In 2000, Dr. Reuben received the Dennis H. Jahnigen Memorial Award for outstanding contributions to education in the field of geriatrics and, in 2008, he received the Joseph T. Freeman Award from the Gerontological Society of America. He was part of the team that received the 2008 John M. Eisenberg Patient Safety and Quality Award for Research – Joint Commission and National Quality Forum, for Assessing Care of the Vulnerable Elderly. In 2012, he received the Henderson award from the American Geriatrics Society.
Dr. Reuben is a past President of the American Geriatrics Society and the Association of Directors of Geriatric Academic Programs. He served for 11 years on the Geriatrics Test Writing Committee for the American Board of Internal Medicine (ABIM) and for 8 years on the ABIM’s Board of Directors, including as Chair from 2010-2011.
In 2012, Dr. Reuben received one of the first CMMI Innovations Challenge awards to develop a model program to provide comprehensive, coordinated care for patients with Alzheimer’s Disease and other dementias. In 2014, he was one of three principal investigators to be awarded a multicenter clinical trial (STRIDE) by the Patient-Centered Outcomes Research Institute (PCORI) and the National Institute on Aging (NIA) to reduce serious falls related injuries; it is the largest grant that PCORI has awarded. In addition to his leadership in geriatrics, Dr. Reuben continues to provide primary care for frail older persons, including making house calls. In his spare time, Dr. Reuben has written four plays and lyrics for more than 20 songs with composer Sidney Sharp. A compilation of the first 10 has been recorded.
STRIDE Study Leadership
NANCY K. LATHAM, PhD
Brigham and Women’s Hospital, Boston
STRIDE Study Director
Lecturer, Harvard Medical School
Assistant Professor, Health and Disability Research Institute, Boston University School of Public Health
Nancy Latham is the Study Director for STRIDE at Partners Healthcare in Boston. She completed her training in Physical Therapy at the University of Toronto and McGill University, a PhD in the area of clinical epidemiology at the University of Auckland, New Zealand and a NIDRR post-doctoral fellowship in Health Services Research at Boston University. She has been the principal investigator or co-investigator of clinical trials investigating exercise and technological interventions to improve function and reduce falls in older adults, as well as observational, meta-analytic and outcome measure development studies. Her most recent trial was HIP Rehab, an RCT of a home-based exercise program for people after hip fracture that was published in JAMA. She also is a faculty member at the Health and Disability Research Institute, Boston University School of Public Health where she conducts research to develop and evaluate the efficacy of new technologies to improve health and quality of life in persons with different disabling conditions. She is a Fellow of the Gerontological Society of America and is currently on the editorial board of Archives of Physical Medicine and Rehabilitation.
PETER N. PEDUZZI, PhD
Director of the Data Coordinating Center
Professor of Public Health (Biostatistics)
Director, Yale Center for Analytical Sciences (YCAS)
Dr. Peduzzi is professor of biostatistics at Yale School of Public Health (YSPH) and Director of YCAS and the BSR of YCC. He serves on the Executive Committee and Protocol Review Committee for YCC. Dr. Peduzzi has more than 30 years’ experience in the design, conduct and analysis of clinical trials and comparative effectiveness studies. Before coming to Yale he was the Director of the Veterans Affairs (VA) Cooperative Studies Program Coordinating Center at the VA Connecticut Healthcare System, West Haven, CT for more than a decade and is still affiliated with this center. His primary research interests have focused on the efficient design and analysis of comparative effectiveness clinical trials and geriatric studies.
SHEZHAD BASARIA, MD
Brigham and Women’s Hospital, Boston,
STRIDE Safety Officer
Medical Director, Section of Men’s Health, Aging and Metabolism,
Brigham and Women’s Hospital, Harvard Medical School
Dr. Basaria is a Reproductive Endocrinologist and board certified in Endocrinology, Diabetes, and Metabolism.
Dr. Basaria is a clinical investigator in the field of male reproductive endocrinology. His research interests include the role of testosterone in pain perception, age-related androgen deficiency and cardiometabolic consequences of androgen deprivation therapy in men with prostate cancer. Dr. Basaria also provides clinical care to patients with male reproductive disorders.
Dr. Basaria is a member of the American Board of Internal Medicine Endocrinology, Diabetes, and Metabolism Board Exam Committee. He is the Associate Editor of the Journal of Gerontology Medical Sciences, and also serves on the editorial boards of the Journal of Clinical Endocrinology and Metabolism and Endocrine Practice. Previously, Dr. Basaria led the section on Male Reproduction on the Self-Assessment Committee of the Endocrine Society. He was also previously involved in developing the Endocrine Society’s Male Androgen Deficiency Performance Improvement Module, which practicing endocrinologists utilize towards their Maintenance of Certification. Dr. Basaria serves as a member of the National Institute of Child Health and Development’s Special Emphasis Panel on Male Contraception.
Dr. Basaria received his medical degree from The Aga Khan University in Karachi, Pakistan. He completed house staff training at The University of Texas Health Science Center at Houston and his endocrine fellowship at The Johns Hopkins University School of Medicine.